MVP Antibody (1032) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248430-Each-of-1 | In Stock | ₹ 46,636.00 |
NBP248430 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,636.00
GST (18%): ₹ 8,394.48
Total Price: ₹ 55,030.48
Antigen
MVP
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
MVP
Immunogen
Proteins precipitated from human breast cancer MCF-7 cells
Quantity
7 mL
Research Discipline
Cancer
Gene ID (Entrez)
9961
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
1032
Dilution
Immunohistochemistry-Paraffin
Gene Alias
LRPVAULT1, Lung resistance-related protein, major vault protein
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- MVP Monoclonal specifically detects MVP in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.