AIF-1/Iba1 Antibody (rAIF1/1909) - Azide and BSA Free, Novus Biologicals™

AIF-1/Iba1

Monoclonal

0.2 mg/ml

Immunohistochemistry-Paraffin 1-2 ug/ml

P55008

AIF1

Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)

Protein A or G purified

Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience

199.0

Human

Purified

Immunohistochemistry (Paraffin)

rAIF1/1909

Unconjugated

10 mM PBS with No Preservative

AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1

Mouse

16.7 kDa

100 μg

Primary

AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

Store at 4°C.

IgG1 κ