HLA G Antibody (2A12), Alexa Fluor™ 594, Novus Biologicals™

HLA G

Monoclonal

Alexa Fluor 594

50 mM sodium borate with 0.05% sodium azide

HLA-G

C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin (NM_002127.5).

Adaptive Immunity, Autoimmune Diseases, Cancer, Developmental Biology, Immunology, Inflammation, Innate Immunity, Virology Bacteria and Parasites

3135

Human

IgG1

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

2A12

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

b2 microglobulin, HLA class I histocompatibility antigen, alpha chain G, HLA class I molecule, HLA G antigen, HLA-6.0, HLAG, HLA-G histocompatibility antigen, class I, G, major histocompatibility complex, class I, G, MHC class I antigen G, MHC-G, sHLA-G

Mouse

0.1 mL

Primary

The antibody 2A12 allows to discriminate between soluble HLA-G protein yielded by shedding from membrane-bound HLA-G forms that do not contain the intron 4-encoded epitope and soluble HLA-G5/HLA-G6 produced from intron 4-retaining alternatively spliced mRNAs. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

Store at 4°C in the dark.