Insulin Antibody (2D11-H5 (same as INS05)), Alexa Fluor™ 532, Novus Biologicals™

Insulin

Monoclonal

Alexa Fluor 532

50 mM sodium borate with 0.05% sodium azide

INS

Purified pig insulin, conjugated to KLH (Uniprot: P01308)

Primary

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Store at 4°C in the dark.

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

2D11-H5 (same as INS05)

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Mouse

0.1 mL

3630

Human, Mouse

IgG1 κ