OPA115619
GRPR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OPA115619-Each-of-1 | In Stock | ₹ 61,588.00 |
OPA115619 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,588.00
GST (18%): ₹ 11,085.84
Total Price: ₹ 72,673.84
Antigen
GRPR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRPR
Gene Alias
BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2925
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P30550
Gene Symbols
GRPR
Immunogen
Synthetic peptide, conjugated to KLH, corresponding to the 2nd extracellular loop of human GRPR.
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Human pancreas, islets of Langerhans
- By immunohistochemistry, OPA1-15619 detects GRPR in formalin fixed, paraffin embedded human tissues
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues
- The effects of GRP are mediated through the gastrin-releasing peptide receptor
- This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway
- The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate
- An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.