PA1064

Caveolin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1064-Each-of-1 In Stock ₹ 53,756.00

PA1064 - Each of 1

₹ 53,756.00

In Stock

Quantity

1

Base Price: ₹ 53,756.00

GST (18%): ₹ 9,676.08

Total Price: ₹ 63,432.08

Antigen

Caveolin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CAV1

Gene Alias

BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100753021, 12389, 25404, 403980, 857

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P33724, P41350, P49817, Q03135

Gene Symbols

CAV1

Immunogen

Synthetic peptide corresponding to residues M(1) S G G K Y V D S E G H L Y T V P(17) C of human CAV1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Hamster, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-064 detects caveolin 1 from human, canine, hamster, mouse, and rat tissues and cells
  • PA1-064 has been successfully used in Western blot and immunoprecipitation procedures
  • By Western blot, this antibody detects an ∽22 kDa protein representing caveolin 1 from rat heart protein extract
  • The PA1-064 immunogen is a synthetic peptide corresponding to residues M(1) S G G K Y V D S E G H L Y T V P(17) C of human CAV1
  • This sequence is completely conserved between human, mouse, canine, bovine, and rat
  • The PA1-064 immunizing peptide (Cat
  • # PEP-146) is available for use in neutralization and control experiments
  • Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes
  • It interacts directly with G-protein alpha subunits and can functionally regulate their activity
  • Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation
  • It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner
  • Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.