UCP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA124894-Each-of-1 | In Stock | ₹ 54,557.00 |
PA124894 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,557.00
GST (18%): ₹ 9,820.26
Total Price: ₹ 64,377.26
Antigen
UCP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ucp1
Gene Alias
AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
101089511, 22227, 24860, 7350
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.3 mg/mL
Formulation
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
P04633, P12242, P25874
Gene Symbols
Ucp1
Immunogen
Synthetic peptide, conjugated to KLH, corresponding to residues 145-159 of human UCP1, with an N-terminal added cysteine.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Feline, Ferret, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-24894 detects UCP1 from human, mouse, and rat samples, and does not cross-react with UCP2 or UCP3
- PA1-24894 is expected to cross react with bovine (93% conserved), canine (93% conserved), Macaque monkey (100% conserved), rabbit (93% conserved), and ovine (93% conserved) due to sequence homology
- By Western Blot this antibody detects a band of approximately 32 kDa
- Positive Control: Brown adipose tissue
- Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins
- UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak
- UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane
- They also reduce the mitochondrial membrane potential in mammalian cells
- Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known
- UCPs contain the three homologous protein domains of MACPs
- This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.