PA129899
Klotho Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA129899-Each-of-1 | In Stock | ₹ 49,573.00 |
PA129899 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,573.00
GST (18%): ₹ 8,923.14
Total Price: ₹ 58,496.14
Antigen
Klotho
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KL
Gene Alias
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16591
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris HCl with 0.2% BSA and 0.05% sodium azide; pH 7.5
Gene Accession No.
O35082
Gene Symbols
KL
Immunogen
Synthetic peptide corresponding to 17 C-terminal residues of mouse Klotho.
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily
- It encodes a type I membrane protein that is abundant in the kidney and brain
- In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility
- Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling
- KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.