PA130675
5-Methylcytosine Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA130675-Each-of-1 | In Stock | ₹ 61,499.00 |
PA130675 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,499.00
GST (18%): ₹ 11,069.82
Total Price: ₹ 72,568.82
Antigen
5-Methylcytosine
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Immunogen
5-methyl cytosine molecule conjugated to KLH.
Quantity
250 μg
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Target Molecule
Chemical
Applications
Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration
3 mg/mL
Formulation
0.15M PBS with no preservative
Host Species
Sheep
Purification Method
purified
Regulatory Status
RUO
Target Species
Chemical
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The use of 7mM NaOH in the IP is crutial
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription
- It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated
- An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes
- Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.