PA1340

CYP1A1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1340-Each-of-1 In Stock ₹ 46,146.50

PA1340 - Each of 1

₹ 46,146.50

In Stock

Quantity

1

Base Price: ₹ 46,146.50

GST (18%): ₹ 8,306.37

Total Price: ₹ 54,452.87

Antigen

CYP1A1

Classification

Polyclonal

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P04798

Gene Symbols

CYP1A1

Immunogen

Purified, His-tagged, full length human P450 1A1 fusion protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Gene

CYP1A1

Gene Alias

AHH; AHRR; aromatic compound inducible; aryl hydrocarbon hydroxylase; CP11; CYP; CYP1; Cyp1a1; Cyp1a-1; Cyp1a2; Cyp45c; Cypc45c; CYPIA1; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; cytochrome P450 family 1 subfamily A member 1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450-C; cytochrome P450MT2; Cytochrome P450MT2A; Cytochrome P450MT2B; Cytochrome P450-P1; dioxin-inducible; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P1-450; P450; P450 form 6; P450-1; P450-C; P450DX; P450form6; P-450MC; P450MT2; P450-P1; xenobiotic monooxygenase

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1543

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PA1-340 detects cytochrome P450 (P450) 1A1 from human cells
  • This antibody detects, to a lesser extent, other P450 isoforms
  • PA1-340 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽54 kDa protein representing P450 1A1 from MCF-7 cell extract
  • The PA1-340 immunogen is purified, His-tagged, full length human P450 1A1 fusion protein
  • This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes
  • The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
  • This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke
  • The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates
  • The gene has been associated with lung cancer risk
  • A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.