PA14146

GABARAP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14146-Each-of-1 In Stock ₹ 52,332.00

PA14146 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

GABARAP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GABARAP

Gene Alias

ATG8A; FLC3B; FLJ25768; GABA type A receptor-associated protein; GABA(A) receptor-associated protein; GABA-A receptor-associated protein; Gabarap; GABARAP a; GABARAP-a; gamma-aminobutyric acid receptor associated protein; gamma-aminobutyric acid receptor-associated protein; gamma-aminobutyric acid reseptor associated protein; HT004; hypothetical protein; MGC120154; MGC120155; MM46

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11337, 58974

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O95166, P60517

Gene Symbols

GABARAP

Immunogen

Synthetic peptide corresponding to residues T(42) R G A P R P P P S S P P(54) of the 105 kDa rat GABA R2 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4146 detects GABA Receptor Associated Protein Subunit 2 in human and rat samples
  • PA1-4146 has been successfully used Western blot procedures
  • By Western blot this antibody detects a ∽105 kDa protein representing GABA Receptor Associated Protein Subunit 2 in brain lysate
  • The PA1-4146 immunogen is a synthetic peptide corresponding to residues T(42) R G A P R P P P S S P P(54) of the 105 kDa rat GABA R2 protein
  • Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system
  • It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC
  • GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton
  • GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.