BAP31 Monoclonal Antibody (CC-4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3-003-Each-of-1 | In Stock | ₹ 51,620.00 |
MA3-003 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
BAP31
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.02% sodium azide
Gene Accession No.
P51572
Gene Symbols
BCAP31
Immunogen
Amino acid residues 123-229 of human BAP31.
Regulatory Status
RUO
Gene ID (Entrez)
100770274, 10134, 533949
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
CC-4
Conjugate
Unconjugated
Gene
BCAP31
Gene Alias
6C6 antigen; 6C6-AG; 6C6-AG tumor-associated antigen; accessory protein BAP31; B cell receptor associated protein 31; BAP31; Bcap31; B-cell receptor-associated protein 31; BCR-associated protein 31; BCR-associated protein Bap31; CDM; CDM protein; DDCH; DXS1357E; hypothetical protein LOC533949; OTTHUMP00000025978; p28; p28 Bap31; Protein CDM
Host Species
Rat
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Hamster, Human, Non-human Primate
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- MA3-003 detects BAP31 from human, non-human primate, bovine and hamster samples
- MA3-003 has been successfully used in Western blot, immunofluorescent, and immunohistochemical procedures
- By Western blot, this antibody detects a 28-kDa protein corresponding to human BAP31
- The MA3-003 antigen is solubilized protein from human neuroendocrine cell line IMR-32, followed by an extract of the small lung human carcinoma cell line SCC-9
- MA3-003 binds to a more proximal region of BAP31 (amino acids 123-229)
- This sequence is conserved in non-human primate, bovine and hamster species
- BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane spanning protein of the endoplasmic reticulum
- It has been shown to form both homo- and hetero-oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL-2/BCL-XL-associated protein
- In the C-terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade
- It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus
- BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator)
- It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.