PA14276
ILP-2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA14276-Each-of-1 | In Stock | ₹ 46,502.50 |
PA14276 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ILP-2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BIRC8
Gene Alias
baculoviral IAP repeat containing 8; baculoviral IAP repeat-containing 8; baculoviral IAP repeat-containing protein 8; BIRC8; hILP2; IAP-like protein 2; ILP2; ILP-2; inhibitor of apoptosis-like protein 2; testis-specific inhibitor of apoptosis
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
112401
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q96P09
Gene Symbols
BIRC8
Immunogen
Synthetic peptide: E(71) E K G H E Y I N N I H L T(84)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-4276 detects the ILP-2 protein in human samples
- PA1-4276 has been successfully used in Western blot procedures
- PA1-4276 immunogen corresponds to amino acid residues 71-84 of the human ILP-2 protein
- Apoptosis, or programmed cell death, is related to many diseases, such as cancer
- Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins
- IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases
- A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2
- ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues
- ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1
- ILP-2 interacts with the processed caspase-9
- These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.