PTGDS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146022-Each-of-1 | In Stock | ₹ 49,439.50 |
PA146022 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
PTGDS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGDS
Gene Alias
21kDa; Beta-trace protein; cerebrin-28; Glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; LPGDS; L-PGDS; PDS; PGD2; PGD2 synthase; PGDS; PGDS2; PH2DISO; Prostaglandin D synthase; prostaglandin D2 synthase; prostaglandin D2 synthase (21 kDa, brain); prostaglandin D2 synthase (brain); prostaglandin D2 synthase 21kDa (brain); prostaglandin-D2 synthase; Prostaglandin-H2 D-isomerase; Ptgds; Ptgs3; testis tissue sperm-binding protein Li 63n
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100067921, 19215, 25526, 286858, 397456, 493852, 5730
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.
O02853, O09114, O97921, P22057, P41222, Q29095, Q29487
Gene Symbols
PTGDS
Immunogen
A synthetic peptide made to a region within residues 25-100 of the human PTGDS protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Equine, Feline, Fish, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody has an 87% sequence homology with ovine and a 82% homology with rabbit
- Suggested positive control: antigen standard for PTGDS (transient overexpression lysate), human brain protein
- The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2)
- PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system
- PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation
- PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier
- Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep
- It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system
- PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease.