PRL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106431-Each-of-1 | In Stock | ₹ 46,858.50 |
PIPA5106431 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,858.50
GST (18%): ₹ 8,434.53
Total Price: ₹ 55,293.03
Antigen
PRL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTP4A1
Gene Alias
AA415290; AU019864; C130021B01; DKFZp779M0721; HH72; PRL1; Prl-1; protein tyrosine phosphatase 4a1; protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA protein 1; protein tyrosine phosphatase type IVA, member 1; protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PTP(CAAX1); PTP(CAAXI); PTP4A1; PTP4A1 protein; PTP4A2; PTPCAAX1; RP5-1148A21.2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19243, 29463, 7803
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q63739, Q78EG7, Q93096
Gene Symbols
PTP4A1
Immunogen
A synthesized peptide derived from human PTP4A1(Accession Q93096), corresponding to amino acid residues N142-Q173.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total PTP4A1/PRL1
- The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif
- PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes
- This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane
- The surface membrane association of this protein depends on its C-terminal prenylation
- Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis
- Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells
- PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase
- PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.