PA14603

Phospho-Synapsin 1 (Ser9) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14603-Each-of-1 In Stock ₹ 46,502.50

PA14603 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-Synapsin 1 (Ser9)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O88935, P09951

Gene Symbols

SYN1

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 of rat SYN1 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat, Zebrafish

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Gene

SYN1

Gene Alias

Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20964, 24949, 570672

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with bovine, human, mouse, Xenopus and zebrafish based on 100% sequence homology
  • In Western blot, this antibody detects an ∽78 kDa protein representing Phospho-Ser9 Synapsin protein
  • It also weakly labels the ∽ 55 kDa Synapsin II protein which has a similar phosphorylation site to that of SER9 on Synapsin I
  • SYN1 (synapsin 1) is a member of the synapsin gene family
  • Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles
  • Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases
  • Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis
  • It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal
  • Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome
  • Alternatively spliced transcript variants encoding different isoforms have been identified.