mGluR1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146151-Each-of-1 | In Stock | ₹ 46,502.50 |
PA146151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
mGluR1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Grm1
Gene Alias
4930455H15Rik; ENSMUSG00000075319; G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member A; glutamate metabotropic receptor 1; glutamate receptor; glutamate receptor, metabotropic 1; Gm10828; GPRC1A; GRM1; GRM1A; Metabotropic glutamate receptor 1; MGLU1; MGLUR1; mGluR1a; nmf373; PPP1R85; protein phosphatase 1, regulatory subunit 85; rcw; SCAR13; wobl
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14816, 24414, 2911, 421614
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P23385, P97772, Q13255
Gene Symbols
Grm1
Immunogen
Synthetic peptide comprising residues 1159-1171 of the human GluR1 protein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Chicken, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: human brain lysate, rat dorsal root ganglion, and rat brain (cingulate cortex), antigen standard for GRIN1 (transient overexpression lysate)
- Glutamate is the main excitatory neurotransmitter in the brain
- For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission
- Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins
- These receptors are called metabotropic glutamate receptors
- In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores
- Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase
- The Group-I receptors include mGluR1a and mGluR5
- The Group-II receptors in include mGluR2 and mGluR3.