OXPAT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146216-Each-of-1 | In Stock | ₹ 48,905.50 |
PA146216 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
OXPAT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Plin5
Gene Alias
2310076L09Rik; AI415325; AW109675; lipid droplet associated protein; lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; LSDA5; LSDP5; Mldp; Myocardial LD protein; Oxpat; Pat1; PAT-1; perilipin 5; perilipin-5; Plin5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
440503, 66968
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1.01 mg/mL
Formulation
PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.
Q00G26, Q8BVZ1
Gene Symbols
Plin5
Immunogen
C-terminal region of the mouse OXPAT protein, with in residues 400-463 [Uniprot# Q8BVZ1].
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The target sequence has 89% sequence homology with rat and 75% sequence homology with bovine
- Suggested positive control: human and mouse heart lysate
- Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues
- Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation
- In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE
- Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets
- Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2
- Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.