PA146018

CIC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA146018-Each-of-1 In Stock ₹ 46,413.50

PA146018 - Each of 1

₹ 46,413.50

In Stock

Quantity

1

Base Price: ₹ 46,413.50

GST (18%): ₹ 8,354.43

Total Price: ₹ 54,767.93

Antigen

CIC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CIC

Gene Alias

1200010B10Rik; Capicua; capicua homolog; capicua homolog (Drosophila); capicua transcriptional repressor; CIC; KIAA0306; mKIAA0306; Protein capicua homolog; protein capicua homolog; LOW QUALITY PROTEIN: protein capicua homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23152, 308435, 484475, 71722

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q924A2, Q96RK0

Gene Symbols

CIC

Immunogen

A synthetic peptide made to a region within residues 1500-1608 of the human Capicua protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • By Western blot, PA1-46018 is specific for the ∽250 kDa CIC protein
  • CIC (∽164 kDa) interacts with Ataxin 1 (∽87 kDa)
  • This may explain the band at 250 kDa (complex).Suggested positive control: Hela whole cell extract
  • This gene encodes a core component of the exosome
  • The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening
  • The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.