STIM1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146217-Each-of-1 | In Stock | ₹ 48,905.50 |
PA146217 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
STIM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STIM1
Gene Alias
D11S4896E; GOK; IMD10; RGD:1306831}; SIM; Stim1; stim1 {ECO:0000312; STIM1L; STRMK; Stromal interaction molecule 1; stromal interaction molecule 1 precursor; TAM; TAM1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20866, 361618, 534816, 608643, 6786
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.
P70302, P84903, Q13586, Q58CP9
Gene Symbols
STIM1
Immunogen
Synthetic peptide made to a C-terminal region with residues 600-685 of the human protein.[Uniprot#Q13586]
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Canine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The target sequence has 93% sequence homology with porcine and 79% sequence homology with xenopus
- Suggested positive control: antigen standard for STIM1 (transient overexpression lysate), HeLa whole cell lysate
- STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane
- Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm
- However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet
- Many questions also remain to be solved around STIM1 functional distribution
- It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.