DARPP-32 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA14650-Each-of-1 | In Stock | ₹ 46,502.50 |
PA14650 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
DARPP-32
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
Q60829, Q6J4I0
Gene Symbols
Ppp1r1b
Immunogen
Synthetic peptide corresponding to the N-terminal region of rat PPP1R1B conjugated to KLH
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene
Ppp1r1b
Gene Alias
AU040756; DARPP32; DARPP-32; dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine and cAMP-regulated neuronal phosphoprotein 32; dopamine- and cAMP-regulated phosphoprotein DARPP-32; FLJ20940; IPPD; neuronal phosphoprotein DARPP-32; OTTHUMP00000164275; OTTHUMP00000164276; Ppp1r1b; PPR1B; protein pho; protein phosphatase 1 regulatory inhibitor subunit 1B; protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1, regulatory (inhibitor) subunit 1B
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19049, 360616
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody is predicted to react with bovine, canine, chicken, human, mouse, non-human primate and Xenopus based on 100% sequence homology
- This antibody is specific for the ∽32 kDa DARPP-32 protein
- DARPP-32 is a dopamine (DA) and AMP-regugated ∽32 kDa phosphoprotein that is associated with dopaminoceptive neurons
- The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34
- In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA
- Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission
- In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac®.