Phospho-MARCKS (Ser152, Ser156) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA14629-Each-of-1 | In Stock | ₹ 49,439.50 |
PA14629 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
Phospho-MARCKS (Ser152, Ser156)
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
P26645, P30009
Gene Symbols
MARCKS
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser152/156 of rat MARCKS conjugated to KLH
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
MARCKS
Gene Alias
80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17118, 25603
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody is predicted to react with bovine, chicken, human, mouse, Xenopus and zebrafish based on 100% sequence homology
- This antibody is specific for the ∽87 kDa MARCKS protein phosphorylated at Ser152 and Ser156 in Western blots of rat brain homogenates
- Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide
- MARCKS is a substrate for protein kinase C
- It is localized to the plasma membrane and is an actin filament crosslinking protein
- Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm
- The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.