PA1737

SCAMP5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1737-Each-of-1 In Stock ₹ 46,502.50

PA1737 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SCAMP5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCAMP5

Gene Alias

hSCAMP5; Sc5; scamp5; scamp5a; Secretory carrier membrane protein 5; secretory carrier membrane protein 5a; secretory carrier membrane protein 5-like; secretory carrier-associated membrane protein 5; wu:fc30b07; zgc:77438

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

65171

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q9JKE3

Gene Symbols

SCAMP5

Immunogen

Synthetic Peptide: C N(217) Q P Q T Q Y S A T P N Y T Y S N(233)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-737 detects secretory carrier membrane protein 5 (SCAMP 5) from rat brain extract
  • PA1-737 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽25 kDa protein representing SCAMP 5 from rat brain extract
  • PA1-737 immunizing peptide corresponds to amino acid residues 217-233 from rat SCAMP 5
  • This sequence is 94% conserved in mouse
  • PA1-737 immunizing peptide (Cat
  • # PEP-152) is available for use in neutralization and control experiments
  • Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes
  • These proteins are implicated to function in membrane trafficking
  • In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis
  • In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles
  • SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail
  • Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats
  • NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex
  • SCAMPs 4 and 5 lack the N-terminal NPF repeats
  • SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain
  • Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.