PA1775
RAB11B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1775-Each-of-1 | In Stock | ₹ 45,968.50 |
PA1775 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
RAB11B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Rab11b
Gene Alias
A730055L17Rik; GTP-binding protein YPT3; H-YPT3; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; RAS oncogene family protein; ras-related protein Rab-11B; YPT3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
611619, 9230
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
Q15907
Gene Symbols
Rab11b
Immunogen
Synthetic peptide corresponding to residues M(1) G T R D D E Y D Y L F K V V L I C(17) of human Rab11.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Canine, Human, Non-human Primate
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-775 detects Rab 11 from human and non-human primate samples
- This antibody detects both A and B isoforms
- PA1-775 has been successfully used in Western blot procedures
- By Western blot, this antibody detects an ∽22 kDa protein representing Rab 11 in CV1, PC3, and HeLa cell extract
- Another less prominent, unknown band is also detected by this antibody at ∽35 kDa
- The PA1-775 immunizing peptide corresponds to amino acid residues 1-17 from human Rab 11
- This sequence is completely conserved in human, mouse and rat and 94% conserved in C
- elegans and amphibians
- This peptide (Cat
- # PEP-195) is available for use in neutralization and control experiments
- Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases
- Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions
- Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP
- Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion
- There exist over 40 Rab proteins that have been described in mammals
- Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.