PA1848

p300 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1848-Each-of-1 In Stock ₹ 50,107.00

PA1848 - Each of 1

₹ 50,107.00

In Stock

Quantity

1

Base Price: ₹ 50,107.00

GST (18%): ₹ 9,019.26

Total Price: ₹ 59,126.26

Antigen

p300

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EP300

Gene Alias

A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2033

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q09472

Gene Symbols

EP300

Immunogen

Synthetic peptide corresponding to residues G(139) T S G P N Q G P T Q S T(151) C in the nuclear factor binding domain of human p300.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-848 detects p300 from human cells
  • PA1-848 has been successfully used in Western blot and ChIP procedures
  • By Western blot, this antibody detects an ∽265 kDa protein representing p300 from HeLa cell lysate
  • The PA1-848 immunogen is a synthetic peptide corresponding to residues G(139) T S G P N Q G P T Q S T(151) C in the nuclear factor binding domain of human p300
  • The PA1-848 immunizing peptide (Cat
  • # PEP-053) is available for use in neutralization and control experiments
  • EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein
  • p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB
  • This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A
  • EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.