RORA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1812-Each-of-1 | In Stock | ₹ 50,018.00 |
PA1812 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,018.00
GST (18%): ₹ 9,003.24
Total Price: ₹ 59,021.24
Antigen
RORA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RORA
Gene Alias
9530021D13Rik; nmf267; NR1F1; Nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR related orphan receptor A; RAR-related orphan receptor A; RAR-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; retinoid-related orphan receptor-alpha; ROR Alpha; ROR1; ROR2; ROR3; Rora; Roralpha; ROR-alpha; RORalpha1; RZRA; RZR-ALPHA; sg; staggerer; thyroid hormone nuclear receptor alpha variant 4; tmgc26; transcription factor RZR-alpha
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
300807, 6095
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P35398
Gene Symbols
RORA
Immunogen
Synthetic peptide corresponding to residues K(541) E L F T S E F E P A M Q I D G(556) of human ROR alpha.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-812 detects human ROR alpha protein in transfected cell samples
- PA1-812 is specific for alpha isotypes
- PA1-812 has successfully been used in Western blot procedures
- By Western blot, this antibody detects an ∽56 kDa protein representing ROR alpha in transfected BL21 cells using a pGEX-hROR alpha1-GST vector
- The PA1-812 immunogen is a synthetic peptide corresponding to residues K(541) E L F T S E F E P A M Q I D G(556) of human ROR alpha
- This peptide (Cat
- # PEP-230) is available for use in neutralization and control experiments
- RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain
- RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function
- Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators
- It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component
- It is widely expressed in most of the tissues
- Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).