PNR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1809-Each-of-1 | In Stock | ₹ 41,385.00 |
PA1809 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
PNR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NR2E3
Gene Alias
A930035N01Rik; ESCS; MGC138414; MGC138416; Nr2e3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; rd7; retinal degeneration 7; Retina-specific nuclear receptor; Rnr; RP11-295F4.5; RP37; taR-5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10002, 100365683
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
Q9Y5X4
Gene Symbols
NR2E3
Immunogen
Synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-809 detects PNR from rat and human samples
- PA1-809 has been successfully used in Western blot procedures
- By Western blot, this antibody detects an ∽42 kDa protein representing PNR from rat tissue extracts
- The PA1-809 immunogen is a synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR
- This sequence is completely conserved between mouse and chicken
- This immunizing peptide (cat
- # PEP-237) can be used for neutralization and control experiments
- NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development
- It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis
- In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration
- A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte
- Two alternatively spliced isoforms have been documented
- NR2E3 is expressed in the retina
- ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.