Ataxin 2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA540131-Each-of-1 | In Stock | ₹ 47,570.50 |
PA540131 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,570.50
GST (18%): ₹ 8,562.69
Total Price: ₹ 56,133.19
Antigen
Ataxin 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Atxn2
Gene Alias
9630045M23Rik; ASL13; ataxin 2; ataxin-2; ATX2; Atxn2; AW544490; FLJ46772; SCA2; spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2); spinocerebellar ataxia 2 homolog; spinocerebellar ataxia type 2 protein; Spinocerebellar ataxia type 2 protein homolog; TNRC13; Trinucleotide repeat-containing gene 13 protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20239, 6311
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.28 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O70305, Q99700
Gene Symbols
Atxn2
Immunogen
Recombinant protein within aa 604-796 of human ATXN2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, HeLa, and HepG2 cells
- Predicted reactivity: Mouse (93%), Xenopus laevis (84%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord
- Clinically, ADCA has been divided into three groups: ADCA types I-III
- Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2)
- SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia
- SCA2 is caused by expansion of a CAG repeat in the coding region of this gene
- Longer expansions result in earlier onset of the disease
- Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.