PA540215

Phospho-HDAC5/HDAC9 (Ser259, Ser220) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540215-Each-of-1 In Stock ₹ 46,057.50

PA540215 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

Phospho-HDAC5/HDAC9 (Ser259, Ser220)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HDAC5

Gene Alias

Antigen NY-CO-9; HD5; HD7; HD7b; HD9; HDAC; HDAC5; HDAC7; HDAC7B; HDAC9; hdac-9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4/5-related protein; histone deacetylase 5; Histone deacetylase 7B; histone deacetylase 9; Histone deacetylase-related protein; KIAA0600; KIAA0744; MEF-2 interacting transcription repressor (MITR) protein; MEF2-interacting transcription repressor MITR; MITR; NY-CO-9

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10014, 15184, 79221, 9734

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q99N13, Q9UKV0, Q9UQL6, Q9Z2V6

Gene Symbols

HDAC5, HDAC9

Immunogen

Synthesized peptide derived from human HDAC5/9 around the phosphorylation site of S259/220.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse based on sequence homology
  • Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4)
  • Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events
  • Histone deacetylases act via the formation of large multiprotein complexes
  • Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C
  • During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors
  • Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.