Phospho-TGFBR1 (Ser165) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA540298-Each-of-1 | In Stock | ₹ 46,413.50 |
PA540298 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Phospho-TGFBR1 (Ser165)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TGFBR1
Gene Alias
AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21812, 29591, 7046
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P36897, P80204, Q64729
Gene Symbols
TGFBR1
Immunogen
Synthesized peptide derived from human TGFbeta RI around the phosphorylation site of S165.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with human and rat based on sequence homology
- TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs
- Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1
- TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm
- The encoded protein is a serine/threonine protein kinase
- Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).