PA540303

Phospho-MLK3 (Ser674) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540303-Each-of-1 In Stock ₹ 46,502.50

PA540303 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-MLK3 (Ser674)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K11

Gene Alias

2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26403, 309168, 4296

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q16584, Q66HA1, Q80XI6

Gene Symbols

MAP3K11

Immunogen

Synthesized peptide derived from human MLK3 around the phosphorylation site of S674.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with human and rat based on sequence homology
  • MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways
  • This kinase contains a SH3 domain and a leucine zipper-basic motif
  • This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway
  • This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.