OBFC2B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA548241-Each-of-1 | In Stock | ₹ 46,502.50 |
PA548241 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
OBFC2B
Classification
Polyclonal
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q8R2Y9, Q9BQ15
Gene Symbols
NABP2
Immunogen
KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human OBFC2B.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
NABP2
Gene Alias
2610036N15Rik; hSSB1; LP3587; Nabp2; nucleic acid binding protein 2; nucleic acid-binding protein 2; Obfc2b; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; RGD1308158; Sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single strand DNA-binding protein 1; single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1; SSB1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
69917, 79035
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- Predicted to react with bovine and rat based on sequence homology
- Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint
- In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines
- The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability
- Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.