IEX-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA548274-Each-of-1 | In Stock | ₹ 46,413.50 |
PA548274 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
IEX-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IER3
Gene Alias
AI663993; anti-death protein; cAMP inducible gene 3; cI-3; DADB-118P11.5; Dif2; DIF-2; differentiation-dependent gene 2 protein; expressed in pancreatic carcinoma; GLY96; gly96, mouse, homolog of; IER3; IEX1; IEX-1; IEX-1L; immediate early protein GLY96; immediate early response 3; immediate early response 3 protein; immediately early gene X-1; Ler3; PACAP-responsive gene 1 protein; PRG1; Protein DIF-2; Protein PRG1; Radiation-inducible immediate-early gene IEX-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15937, 8870
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P46694, P46695
Gene Symbols
IER3
Immunogen
KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human IER3.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- IEX-1 is a stress inducible gene that is induced by ionizing radiation, μgtraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a
- IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium
- It plays an important role in the regulation of cellular growth, cell death and oncogenesis
- IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappa-B/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions
- IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S
- It is localized to the nucleus and perinuclear region
- Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.