PA549085

B7-H6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549085-Each-of-1 In Stock ₹ 46,502.50

PA549085 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

B7-H6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NCR3LG1

Gene Alias

B7 homolog 6; B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; NCR3LG1; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

374383

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q68D85

Gene Symbols

NCR3LG1

Immunogen

KLH conjugated synthetic peptide between 389-415 amino acids from the C-terminal region of human B7H6.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells
  • B7-H6 binds with NKp30 present on NK cells
  • Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis
  • B7-H6 is not constitutively expressed on normal tissue
  • Whether it can be expressed endogenously under certain conditions is under investigation
  • B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.