PA549320

CGREF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549320-Each-of-1 In Stock ₹ 46,502.50

PA549320 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CGREF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CGREF1

Gene Alias

1110004G24Rik; AW045201; cell growth regulator with EF hand domain 1; cell growth regulator with EF hand domain protein 1; cell growth regulator with EF-hand domain 1; cell growth regulatory gene 11 protein; cell growth regulatory with EF-hand domain; CGR11; Cgref1; Hydrophobestin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

245918

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P97586

Gene Symbols

CGREF1

Immunogen

KLH conjugated synthetic peptide between 220-248 amino acids from the C-terminal region of rat Cgref1.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

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Description

  • CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion
  • Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines
  • CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome
  • Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes
  • Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.