PA549750
Cyclin L1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA549750-Each-of-1 | In Stock | ₹ 46,502.50 |
PA549750 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Cyclin L1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ccnl1
Gene Alias
2610030E23Rik; ANIA6A; ania-6a; AU018493; BM-001; Ccn1; Ccnl; CCNL1; Cyclin Ania-6a; cyclin L ania-6a; cyclin L gamma; cyclin L1; cyclin-L; Cyclin-L1; LOW QUALITY PROTEIN: cyclin-L1; PRO1073; UNQ530/PRO1073
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
114121, 56706, 57018
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q52KE7, Q9R1Q2, Q9UK58
Gene Symbols
Ccnl1
Immunogen
Synthesized peptide derived from human Cyclin-L1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total Cyclin L1 protein
- FUS/TLS was originally described as fused in Sarcoma is actually related to a number of different cellular processes and correlated to several diseases
- FUS binds DNA as a single or double strand, and acts as a site for transcription factors to recognize
- Since FUS is well-documented to be involved in liposarcoma, lipoma and leukaemia, it is believed that when its normal housekeeping functions related to transcription are disrupted, normal cells become cancerous
- Interestingly, FUS is also associated with the fatal neuron disorder amyotrophic lateral sclerosis; interruption of its normal RNA-binding functions leads to incorrect cellular localization and leads to pathologies of the neuron
- Thus, FUS regulation of cellular functions is a critical component of maintenance of healthy cells.