MASTL Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550180-Each-of-1 | In Stock | ₹ 48,727.50 |
PA550180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,727.50
GST (18%): ₹ 8,770.95
Total Price: ₹ 57,498.45
Antigen
MASTL
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MASTL
Gene Alias
2700091H24Rik; C88295; GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; Mastl; MAST-L; microtubule associated serine/threonine kinase like; microtubule associated serine/threonine kinase-like; microtubule-associated serine/threonine-protein kinase-like; RP11-85G18.2; Serine/threonine-protein kinase greatwall; THC2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
84930
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q96GX5
Gene Symbols
MASTL
Immunogen
Synthesized peptide derived from C-terminal of human MASTL.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total MASTL protein
- MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group
- MASTL promotes mitotic progression and cell cycle reentry after DNA damage
- Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta
- Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers
- Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2
- Alternatively spliced transcript variants have been described for this locus.