PA550337

IDH3B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550337-Each-of-1 In Stock ₹ 46,502.50

PA550337 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

IDH3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Idh3b

Gene Alias

C78231; DH3B; H-IDHB; H-IDHG; IDH3B; Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) beta; isocitrate dehydrogenase 3 (NAD+) beta; isocitrate dehydrogenase 3 beta; isocitric dehydrogenase subunit beta; N14A tumor-related protein; NAD(+)-specific ICDH subunit beta; NAD+-specific isocitrate dehydrogenase b subunit; RP46

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170718, 3420

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.2 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O43837

Gene Symbols

Idh3b

Immunogen

Fusion protein corresponding to residues near the C terminal of human isocitrate dehydrogenase 3 (NAD+) gamma

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total IDH3B protein
  • Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate
  • These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+)
  • Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic
  • NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle
  • Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit
  • The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase
  • Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.