CATSPER1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550372-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550372 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CATSPER1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CATSPER1
Gene Alias
cation channel of sperm 1; cation channel sperm associated 1; cation channel sperm-associated protein 1; cation channel, sperm associated 1; CATSPER; CATSPER1; hCatSper; KSper; sperm ion channel; sperm protein CATSPER1; sperm-associated cation channel 1; SPGF7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
117144
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1.8 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q8NEC5
Gene Symbols
CATSPER1
Immunogen
Fusion protein corresponding to residues near the C terminal of human cation channel, sperm associated 1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total CATSPER1 protein
- Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte
- Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2
- The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers
- Sperm capacitation enhances the effect of progesterone by providing additional negative shift
- Also activated by the elevation of intracellular pH.