SPAG6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550556-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550556 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SPAG6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SPAG6
Gene Alias
axoneme central apparatus protein; CT141; PF16; protein PF16 homolog; Repro-SA-1; RGD1310892; SPAG6; Spag6l; sperm associated antigen 6; sperm associated antigen 6 like; sperm flagellar protein; Sperm-associated antigen 6; testicular tissue protein Li 176
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
381350, 9576
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
0.8 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O75602, Q9JLI7
Gene Symbols
SPAG6
Immunogen
Synthetic peptide corresponding to residues near the N terminal of human sperm associated antigen 6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total SPAG6 protein
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization
- Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens
- The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man
- This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions
- Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm
- Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.