PA550398

DRG1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550398-Each-of-1 In Stock ₹ 48,104.50

PA550398 - Each of 1

₹ 48,104.50

In Stock

Quantity

1

Base Price: ₹ 48,104.50

GST (18%): ₹ 8,658.81

Total Price: ₹ 56,763.31

Antigen

DRG1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DRG1

Gene Alias

AA408859; AI132520; developmentally regulated GTP binding protein 1; developmentally regulated GTP-binding protein 1; developmentally-regulated GTP-binding protein 1; Drg; Drg1; DRG-1; GTP-binding protein; NEDD3; NEDD-3; neural precursor cell expressed developmentally down-regulated protein 3; neural precursor cell expressed, developmentally down-regulated 3; TRAFAC GTPase DRG1; Translation factor GTPase DRG1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13494, 4733

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.3 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P32233, Q9Y295

Gene Symbols

DRG1

Immunogen

Fusion protein corresponding to residues near the C terminal of human developmentally regulated GTP binding protein 1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total DRG1 protein
  • Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155)
  • Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions (PubMed:23711155)
  • When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238)
  • Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition
  • GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639)
  • [UniProt]