FAT4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550587-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550587 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
FAT4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FAT4
Gene Alias
6030410K14Rik; 9430004M15; Cadherin family member 14; cadherin-related family member 11; CDHF14; CDHR11; FAT atypical cadherin 4; FAT tumor suppressor homolog 4; FAT tumor suppressor homolog 4 (Drosophila); FAT4; Fatj; FAT-J; fat-like cadherin protein FAT-J; hFat4; HKLLS2; Nbla00548; protocadherin Fat 4; putative protein product of Nbla00548; RGD1564291; VMLDS2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
79633
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.7 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q6V0I7
Gene Symbols
FAT4
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human FAT tumor suppressor homolog 4 (Drosophila)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total FAT4 protein
- FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP)
- FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by secretase to release intracellular domain (ICD)
- FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1
- FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.