PA550801

TBC1D22A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550801-Each-of-1 In Stock ₹ 46,502.50

PA550801 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TBC1D22A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TBC1D22A

Gene Alias

BC023106; C22orf4; D15Ertd781e; HSC79E021; putative GTPase activator; RGD1306588; TBC1 domain family member 22A; TBC1 domain family, member 22a; TBC1D22A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25771

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.4 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q8WUA7

Gene Symbols

TBC1D22A

Immunogen

Fusion protein of human TBC1 domain family, member 22A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total TBC1D22A protein
  • TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members
  • Multiple isoforms of TBC1D22A exist due to alternative splicing events
  • The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome
  • Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia
  • Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.