PA551002

ZAK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551002-Each-of-1 In Stock ₹ 46,858.50

PA551002 - Each of 1

₹ 46,858.50

In Stock

Quantity

1

Base Price: ₹ 46,858.50

GST (18%): ₹ 8,434.53

Total Price: ₹ 55,293.03

Antigen

ZAK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K20

Gene Alias

AV006891; AZK; B230120H23Rik; HCCS4; HCCS-4; Human cervical cancer suppressor gene 4 protein; leucine zipper- and sterile alpha motif kinase ZAK; Leucine zipper- and sterile alpha motif-containing kinase; Map3k20; Mitogen-activated protein kinase kinase kinase 20; Mitogen-activated protein kinase kinase kinase MLT; mixed lineage kinase 7; mixed lineage kinase with a leucine zipper and a sterile alpha motif; mixed lineage kinase-related kinase; mixed lineage kinase-related kinase MRK-beta; MLK7; mLklak; MLK-like mitogen-activated protein triple kinase; MLK-related kinase; MLT; MLTK; MLTKalpha; MLTKbeta; MRK; pk; RGD1561394; SFMMP; sterile alpha motif and leucine zipper containing kinase AZK; sterile alpha motif- and leucine zipper-containing kinase AZK; sterile-alpha motif and leucine zipper containing kinase AZK; ZAK

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51776, 65964

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9ESL4, Q9NYL2

Gene Symbols

MAP3K20

Immunogen

Synthesized peptide derived from the C-terminal region of human MLTK.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • ZAK Polyclonal Antibody detects endogenous levels of ZAK protein
  • ZAK is a leucine zipper-containing mitogen-activated protein related to the MLKs in both sequence and function
  • Like the MLKs and other MAP3Ks, ZAK activates MAP2Ks
  • ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif
  • This magnesium-binding protein forms homodimers and is located in the cytoplasm
  • The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells
  • The protein also has pro-apoptotic activity
  • Alternate transcriptional splice variants, encoding different isoforms, have been characterized.