PA551170

WSB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA551170-Each-of-1 In Stock ₹ 46,502.50

PA551170 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

WSB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WSB1

Gene Alias

1110056B13Rik; 2700038M07Rik; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box containing 1; WD repeat and SOCS box-containing 1; WD repeat and SOCS box-containing protein 1; WD repeat and SOCS box-containing protein 1-like protein; WD-40-repeat-containing protein with a SOCS box 1; WSB1; WSB-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26118

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.3 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9Y6I7

Gene Symbols

WSB1

Immunogen

Fusion protein of human WSB1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA550361

--

Img

Thermo Scientific

PA551239

--

Img

Thermo Scientific

PA550897

--

Img

Thermo Scientific

PA551148

--

Img

Thermo Scientific

PA550865

--

Img

Thermo Scientific

PA551164

--

Img

Thermo Scientific

PA551166

--

Img

Thermo Scientific

PA550324

--

Description

  • The antibody detects endogenous levels of total WSB1 protein
  • WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats
  • Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2
  • Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.