PA551225
RHEBL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA551225-Each-of-1 | In Stock | ₹ 46,502.50 |
PA551225 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
RHEBL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RHEBL1
Gene Alias
1810036J22Rik; GTPase RhebL1; ras GTPase; Ras homolog enriched in brain like 1; Ras homolog enriched in brain like 1 c; ras homolog enriched in brain like-1 c; Ras homolog enriched in brain-like 1; ras homolog enriched in brain-like protein 1; RHEB like 1; Rheb2; RHEBL1; RHEBL1c; rheb-like protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
121268
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.6 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q8TAI7
Gene Symbols
RHEBL1
Immunogen
Fusion protein of human RHEBL1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total RHEBL1 protein
- RhebL1 (ras homolog enriched in brain-like protein 1), also known as Rheb2 or GTPase RhebL1, is a 183 amino acid protein that belongs to the small GTPase superfamily and Rheb family
- Localizing to the cell membrane as well as the cytoplasm, RhebL1 is ubiquitously expressed and is increased two-fold in many tumor cell lines
- RhebL1 exhibits GTPase activity and may activate NF-kappa-B-mediated gene transcription
- Regulating the activity of Rictor, RhebL1 also promotes signal transduction
- RhebL1 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 12q13.12 and mouse chromosome 15 F1
- Human chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome
- Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders
- Binds GTP and exhibits intrinsic GTPase activity
- May activate NF-kappa-B-mediated gene transcription
- Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.