PC176100UL

MilliporeSigma™ anti-Serotonin 2A (5-HT2A) Receptor (22-41), Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 PC176100UL-Each-of-1 In Stock ₹ 58,960.72

PC176100UL - Each of 1

₹ 58,960.72

In Stock

Quantity

1

Base Price: ₹ 58,960.72

GST (18%): ₹ 10,612.93

Total Price: ₹ 69,573.65

Antigen

Serotonin 2A (5-HT2A) Receptor (22-41)

Classification

Polyclonal

Formulation

In 150mM NaCl, 20mM sodium phosphate, 1% BSA, pH 7.5.

Immunogen

a synthetic peptide corresponding to amino acids 22-41 of rat 5-HT2Areceptor

Regulatory Status

RUO

Test Specificity

Recognizes the ∽53kDa serotonin 2A (5-HT2A) receptor.

Content And Storage

−20°C

Applications

Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat, Sheep

Form

Liquid

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Description

  • Specifically detects Serotonin 2A (5-HT 2A ) Receptor (22-41) Clone: in Mouse, Rat, Sheep samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting At least 14 mammalian serotonin receptor subtypes have been identified and classified into several families on the basis of common structural, pharmacological, and functional criteria
  • Serotonin (5-hydroxytryptamine [5-HT]) mediates its effects in a number of physiological processes including anxiety, depression, sexual activity, and sleep through interactions with different receptor subtypes
  • These receptors differ in their tissue and cellular localization, affinity for serotonin, and second messenger pathways
  • The majority of these receptors stimulate a GTP-binding protein upon agonist stimulation and couple to adenylate cyclase or phospholipase C
  • In contrast, the serotonin 5-HT 3 receptor acts as a cation-selective channel
  • The serotonin receptors have generated considerable pharmacological interest as targets for the identification of selective drugs that interact with a specific receptor subtype.