PI701238
ApoC3 Recombinant Rabbit Monoclonal Antibody (6H21L11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI701238-Each-of-1 | In Stock | ₹ 51,798.00 |
PI701238 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,798.00
GST (18%): ₹ 9,323.64
Total Price: ₹ 61,121.64
Antigen
ApoC3
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P02656, P06759
Gene Symbols
APOC3
Immunogen
Peptide corresponding to amino acids 37–48 of human Apolipoprotein C3
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
6H21L11
Conjugate
Unconjugated
Gene
APOC3
Gene Alias
Apoc3; APOCIII; Apo-CIII; apoC-III; Apolipoprotein; Apolipoprotein C3; apolipoprotein C-3; apolipoprotein C-III; HALP2; MGC150353
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
24207, 345
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with mouse, non-human primate and rabbit based on sequence homology
- Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene
- Apo-CIII is a component of very low density lipoprotein (VLDL)
- APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles
- The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes
- The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed
- An increase in apoC-III levels induces the development of hypertriglyceridemia.