HRI Recombinant Rabbit Monoclonal Antibody (7H3L3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI702551-Each-of-1 | In Stock | ₹ 57,360.50 |
PI702551 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,360.50
GST (18%): ₹ 10,324.89
Total Price: ₹ 67,685.39
Antigen
HRI
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
Q9BQI3
Gene Symbols
EIF2AK1
Immunogen
Protein corresponding to human elF2AK1 / Heme regulated inhibitor (HRI) (aa271-630)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
7H3L3
Conjugate
Unconjugated
Gene
EIF2AK1
Gene Alias
EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1; eukaryotic translation initiation factor 2-alpha kinase 1; HCR; he; heme regulated initiation factor 2 alpha kinase; heme sensitive initiation factor 2a kinase; heme-controlled repressor; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; heme-regulated inhibitor; heme-regulated initiation factor 2-alpha kinase; heme-regulated repressor; hemin-sensitive initiation factor 2a kinase; hemin-sensitive initiation factor 2-alpha kinase; Hri; KIAA1369; PRO1362
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
27102
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with Monkey, Horse, Mouse Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis
- In the case of EIF2AK1, signaling is initiated by low levels of heme
- The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1
- The two genes are transcribed from opposite strands and kinase activity is induced by low levels of heme and inhibited by the presence of heme.