PI710340

TIMP4 Recombinant Polyclonal Antibody (13HCLC), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI710340-Each-of-1 In Stock ₹ 44,544.50

PI710340 - Each of 1

₹ 44,544.50

In Stock

Quantity

1

Base Price: ₹ 44,544.50

GST (18%): ₹ 8,018.01

Total Price: ₹ 52,562.51

Antigen

TIMP4

Classification

Recombinant Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q99727

Gene Symbols

TIMP4

Immunogen

proprietary

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone

13HCLC

Conjugate

Unconjugated

Gene

TIMP4

Gene Alias

Metalloproteinase inhibitor 4; TIMP 4; TIMP metallopeptidase inhibitor 4; TIMP4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7079

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3
  • It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases
  • Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix
  • TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor
  • The netrin domain of TIMP4 is involved in platelet recruitment and aggregation
  • Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.